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PhD and Postdoc Publications


µMap Photoproximity Labeling Enables Small Molecule Binding Site Mapping, Sean W. Huth, James V. Oakley,Ciaran P. Seath, Jacob B. Geri, Aaron D. Trowbridge, Dann L. Parker, Jr., Frances P. Rodriguez-Rivera, Adam G. Schwaid, Carlo Ramil, Keun Ah Ryu, Cory White, Olugbeminiyi O. Fadeyi, Rob C. Oslund, David W. C. MacMillan, J. Am. Chem. Soc. 2023, 145, 16289-16296.


A Chiral Amine Transfer Approach to the Photocatalytic Asymmetric Synthesis of α-Trialkyl- α-tertiary Amines, Georgia R. Harris, Aaron D. Trowbridge, Matthew J. Gaunt, Org. Lett., 2023, 25, 861–866.


Small Molecule Photocatalysis enables Drug Target Identification via Energy Transfer, Aaron D.Trowbridge*, Ciaran P. Seath*, Frances P. Rodriguez-Rivera*, Beryl X. Li, Barbara E. Dul, Adam G. Schwaid, Benito Buksh, James V. Oakley, Jacob B. Geri, Olugbeminiyi O. Fadeyi, Rob C. Oslund, Keun Ah Ryu, Cory White, Tamara Reyes-Robles, Paul Tawa, Dann L. Parker, Jr., David W. C. MacMillan, Proc. Nat. Acad. Sci., 2022, 119, e2208077119


Thiol-Mediated a-Amino Radical Formation via Visible-Light-Activated Ion-Pair Charge-Transfer Complexes, Keishi Kohara, Aaron Trowbridge, Milo A. Smith, Matthew J. Gaunt, J. Am. Chem. Soc. 2021, 143, 19258–19274


Reactive Intermediates of Interactome Mapping, C. P. Seath, A. Trowbridge, T. W. Muir, D. W. C. MacMillan, Chem. Soc. Rev. 2021, 50, 2911–2926


New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines, A. Trowbridge, S. M. Walton, M. J. Gaunt, Chem. Rev. 2020, 120, 2613–2692


Rapid Syntheses of (–)-FR901483 and (+)-TAN1251C Enabled by Complexity-Generating Photocatalytic Olefin Hydroaminoalkylation, D. Reich, A. Trowbridge, M. J. Gaunt, Angew. Chem. Int. Ed. 2020, 59, 2256– 2261.


Streamlined Synthesis of C(sp3)-Rich N-Heterospirocycles Enabled by Visible-Light-Mediated Photocatalysis, N. J. Flodén, A. Trowbridge, D. Willcox, S. M. Walton, Y. Kim, M. J. Gaunt, J. Am. Chem. Soc. 2019, 141, 8426–8430


Multicomponent Synthesis of Tertiary Alkylamines by Photocatalytic Olefin-Hydroaminoalkylation, A. Trowbridge, D. Reich, M. J. Gaunt, Nature 2018, 561, 522–527


The α-Tertiary Amine Motif Drives Remarkable Selectivity for Pd-Catalyzed Carbonylation of β- methylene C–H bonds, A. Trowbridge*, K. F. Hogg*, A. Alvarez-Pérez, M. J. Gaunt, Chem. Sci. 2017, 8, 8198–8203


Selective Palladium(II)-Catalyzed Carbonylation of Methylene β-C−H Bonds in Aliphatic Amines, J. Cabrera-Pardo, A. Trowbridge, M. Nappi, K. Ozaki, M. J. Gaunt, Angew. Chem. Int. Ed. 2017, 56, 11958–11962


Synthesis of cis-C-Iodo-N-Tosyl-Aziridines using Diiodomethyllithium: Reaction Optimization, Product Scope and Stability, and a Protocol for Selection of Stationary Phase for Chromatography, T. Boultwood, D. Affron, A. Trowbridge, J. Bull, J. Org. Chem. 2013, 78, 6632–6647

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